Abstract Here we systematically investigated genomic alterations from the initiation of induced pluripotent stem (iPS) cell generation to induced mesenchymal stromal/stem Umbrellas cell differentiation.We observed a total of ten copy number alterations (CNAs) and five single-nucleotide variations (SNVs) during the phases of reprogramming, different
We investigate the role and performance of imitative behavior in a class of quantity-setting, Cournot games.Within a framework of evolutionary competition between rational, myopic best-response and imitation heuristics with differential heuristics’ Dog Supplies costs, we found that the equilibrium stability depends on the sign of the cost differe
The evolution of anisogamy or gamete size dimorphism is a fundamental transition in evolutionary history, and it is the origin of the female and male sexes.Although mathematical models attempting to explain this transition have been published as early as 1932, the 1972 model of Parker, Baker, and Smith is considered to be the first explanation for
Pancreatic ductal adenocarcinoma Vitamin K (PDAC) poses a significant threat due to its tendency to evade early detection, frequent metastasis, and the subsequent challenges in devising effective treatments.Processes that govern epithelial-mesenchymal transition (EMT) in PDAC hold promise for advancing novel therapeutic strategies.SAMD1 (SAM domain